The Problem of Cervix Cancer
Cervical cancer is the fourth most common cancer in women globally, with an estimated 6 lac new cases and 3.4 lac deaths in 2020. In India it is 2nd most common and 2nd most common cancer related mortality cancer in females. In >90% cases cervical cancer is caused by persistent infection with the human papillomavirus (HPV), a common sexually transmitted infection that can affect the skin, genital area and throat. Most HPV infections are harmless and clear up on their own, but some high-risk types can cause abnormal cells to develop in the cervix, which can eventually turn into cancer if left untreated. HPV also a common cause of precancerous lesion i.e. lesions which can turn into cancer on long term. In countries with robust screening preventive measures like pap smear and HPV vaccination, the incidence of cervical cancer increased up to age 35 years and thereafter remained approximately constant at relatively low levels. Conversely, in countries with inappropriate screening and vaccination, the incidence increased sharply with age, peaking at around age 55–64 years. Study Link
What HPV vaccine Does ?
HPV vaccine develop antibodies against HPV virus which provide immunity against diseases caused by HPV virus
How to Take HPV Vaccine?
- WHO advise to vaccinate > 90% girls before 15 years.
- two doses of cervix cancer vaccine between age 9-14 years
- three doses between age 15-26 years
- Can be received upto 45 years age
Dose & Schedule of HPV vaccine
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Important Advise
Screening for cervical cancer should continue despite vaccination as recommended i.e. Pap Smear every 3 years or Pap with HPV every 5 years in 21-65 years
